After celebrating Doug's upcoming wedding in a cut rate hotel in Laughlin, NV, hungover guys Bradley, Ed and Zach wake up in a futuristic dystopia, having lost their pal, Doug. With the help of Effing and Justmitch, the trio's loyal advisers, the gang must now prepare to battle their way through the pop culture districts of The Hungover Games including The Real Housewives of District 8 and Teddy from The Puppet District.

After a stint in a psychiatric hospital, a young woman returns to the house where her father killed the entire cast of The Artist during his exorcism.